beta amyloid protein造句

• Eventually, the plaques fill up with these beta amyloid proteins.
• But, Davies said, beta amyloid protein cannot be the entire story.
• Big hopes also rest on secretase inhibitors, designed to prevent the beta amyloid protein forming in the first place.
• Glenner pointed the way to molecular biologists in 1984 with a seminal publication in which he analyzed the purified beta amyloid protein linked to Alzheimer's disease.
• It is believed that crenezumab works by causing beta amyloid proteins to transition from an insoluble to a soluble form, inhibiting aggregation and promoting disaggregation of existing plaques.
• Zimmerman, who hopes to conduct clinical studies on the A-beta amyloid protein, said evidence suggests that preventing its formation in the brain could ward off Alzheimer's.
• The mouse model is based on the observation that the brains of Alzheimer's patients, when autopsied after death, are riddled with plaques of a material called beta amyloid protein.
• In patients given clioquinol, the progression of the disease slowed down and levels of beta amyloid protein, which clumps together to form the plaques, were significantly reduced, it says.
• It is proposed that the aggregation and deposition of the Beta amyloid protein, interferes with the metabolism of neurones and further damages the cholinergic axons in the cortex and cholinergic neurones in the basal forebrain.
• In February, scientists from Athena Neurosciences, for example, reported in the journal Nature that they had bred a mouse whose brain accumulates the beta amyloid protein plaques that are a hallmark of the disease.
• So far, there are no results from the British trial, which is designed to show both whether the vaccine has harmful side effects and whether it causes persons who receive it to build up antibodies to the beta amyloid protein.
• The lab will work to develop technology that can detect substances like the A-beta amyloid protein, said A . Nadeem Ishaque, manager of R & AMP; D's two-month-old Genomics & AMP; Molecular Imaging Laboratory.
• This hypothesis is supported by the observation that higher levels of a variant of the beta amyloid protein known to form fibrils faster " in vitro " correlate with earlier onset and greater cognitive impairment in mouse models and with AD diagnosis in humans.
• Over 1, 000 persons attending the conference sat in silence while Schenk showed slides of brain tissues of mice before and after receiving the vaccine, which has been designated " AN-1792 " and is a synthetic form of the naturally occurring beta amyloid protein.